JAMA 274 "Product Information. Elsevier; 2022. https://www.clinicalkey.com. (1979): 425-6, Shapiro SR "Hypertension due to anorectic agent." (1990): 287-8. Vistaril (hydroxyzine)." Dramamine (dimenhydrinate)." Pharmacia and Upjohn (2001): "Product Information. (1993): 825-7. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. If you notice other effects not listed above, contact your doctor or pharmacist. excitement (especially in children) More serious side effects can occur if you overdose on this . Our phase IV clinical studies alone cannot establish cause-effect relationship. Therapy with sympathomimetic agents should generally be avoided or administered cautiously in patients with sensitivity to sympathomimetic amines, hyperthyroidism, or underlying cardiovascular or cerebrovascular disorders. (2001). One of the more significant ones is cognitive impairment, such as confusion, that's similar to what occurs with dementia or delirium. Warnings: One ingredient in this product is acetaminophen. (1984): 481-5, Forrest JA, Adriaenssens P, Finlayson ND, Prescott LF "Paracetamol metabolism in chronic liver disease." Most likely there is zero correlation, but I have a high tolerance for alc and weed, caffeine doesn't affect me to the same level of others. (2001): "Product Information. These can increase respiratory depression and thicken bronchial secretions. Evidenced-based review and evaluation of clinical significance: Nonpharmacological and pharmacological treatment of insomnia in the elderly. Avoid alcohol. American geriatrics society 2019 updated AGS Beers Criteria for potentially inappropriate medication use in older adults: 2019 AGS Beers Criteria update expert panel. Lower initial dosages may be appropriate. If any of these effects last or get worse, contact your doctor or pharmacist promptly. Lancet 2 This medication may interfere with certain urine lab tests (such as 5-HIAA levels), possibly causing false test results. (1983): 737-8, Noble R "A controlled clinical trial of the cardiovascular and psychological effects of phenylpropanolamine and caffeine." Covington TR, eds., Lawson LC, Young LL "Handbook of Nonprescription Drugs." Dimetane (brompheniramine)." For thousands of years, people have been combining substances in an effort to achieve a greater high. According to Pain Community Centre, as far back as the 1600s, morphine was sometimes combined with alcohol and cocaine in an effort to intensify morphines opiate effects. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Hepatology 22 Applicable conditions: Diabetes Mellitus. (1983): 970, McEwen J "Phenylpropanolamine-associated hypertension after the use of "over- the-counter" appetite-suppressant products." NyQuil Cold and Flu. (2001): "Product Information. Please contact your doctor or pharmacist. Eclat Pharmaceuticals Brandon Peters, MD, is a board-certified neurologist and sleep medicine specialist. J Pediatr 123 Does Dramamine Less Drowsy interact with other medications? Many unintended overdoses have occurred due to opiates across the United States. Drug Metab Dispos 3 Pharmacotherapy for insomnia in adults. Their plasma clearance may be decreased and their half-life prolonged in patients with impaired hepatic function. Moderate Potential Hazard, Moderate plausibility. Daily alcohol use, especially when combined with acetaminophen, may damage your liver. How safe is it?" Am J Emerg Med 4 Chicago, IL: American Medical Association; Arch Intern Med 141 Moderately clinically significant. Placidyl (ethchlorvynol)." People with liver problems and children should take less acetaminophen. Dramamine is an antihistamine that reduces the effects of natural chemical histamine in the body. (1982): 311-5, Kroenke K, Omori DM, Simmons JO, Wood DR, Meier NJ "The safety of phenylpropanolamine in patients with stable hypertension." Postgrad Med 79 The use of the eHealthMe site and its content is at your own risk. If you are using a liquid form, carefully measure your prescribed dose using a medication-measuring device or spoon. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. This means that the medication acts on the signaling chemical called acetylcholine, which can have important consequences. Sonata (zaleplon)." One ingredient in this product is acetaminophen. If you need surgery, tell the surgeon ahead of time if you have taken Dramamine in the past few days. Those who abuse opiates with potentiators can be helped with recommended and proven medical treatments. Today, many people try to combine opiate-based substances with other substances to maximize the euphoric effects. The study is based on acetaminophen / dextromethorphan / doxylamine / pseudoephedrine and dimenhydrinate (the active ingredients of Nyquil and Dramamine, respectively). "Product Information. (1978): 283-6, Clements JA, Critchley JA, Prescott LF "The role of sulphate conjugation in the metabolism and disposition of oral and intravenous paracetamol in man." Clin Ther. (1990): s51-2, Biban P, Baraldi E, Pettennazzo A, Filippone M, Zacchello F "Adverse effect of chloral hydrate in two young children with obstructive sleep apnea." While sleeping pills are one option, cognitive behavioral therapy for insomnia (CBTI) may be the best option without the risk of any medication side effects. They could even trigger a seizure for the first time. cough comes back or occurs with rash or headache that lasts. Br J Clin Pharmacol 50 Sometimes, potentiators are used to intensify the effects of opiates. Rochon PA. Drug prescribing for older adults. (1968): 1031-4, Porter CC, Arison BH, Gruber VF, Titus DC, Vandenheuvel WJ "Human metabolism of cyproheptadine." 2017;85(1):3-17. doi:10.1177/0091415016685330. If you are on a schedule, use the missed dose as soon as you remember. Moderate Potential Hazard, Moderate plausibility. Palpitations, tachycardia, arrhythmia, hypertension, reflex bradycardia, coronary occlusion, cerebral vasculitis, myocardial infarction, cardiac arrest, and death have been reported. (1986): 529-33, Albert KS, Hallmark MR, Sakmar E, Weidler DJ, Wagner JG "Pharmacokinetics of diphenhydramine in man." In: Principles and Practice of Sleep Medicine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. We comply with the HONcode standard for trustworthy health information. Medications for itching, such as hydroxyzine and diphenhydramine (brand names Vistaril and Benadryl). Personalize this study to your gender and age, Propofol and Hydrocortisone Valerate drug interaction, Dementia Alzheimer'S Type and drugs of ingredients of estradiol, Neuropathy Peripheral and Aortic Arch Syndrome. Physical Medicine and Rehabilitation Clinics of North America. Do not use in larger or smaller amounts or for longer than recommended. Dimetapp is known to increase the high felt when taken with opioid medications and illicit drugs. other information we have about you. These medications may cause some risk when taken together. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Some medicines can cause unwanted or dangerous effects when used together. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. (1981): 715, Maher LM, Peterson PL, Dela-Cruz C "Postpartum intracranial hemorrhage and phenylpropanolamine use" Neurology 37 10, FD&C Blue No. Review/update the Evidence suggests diphenhydramine may result in serious side effects in adults ages 65 and older. (1999): 158-60. Closer monitoring of blood glucose concentrations may be appropriate. The opiate elements can be extracted with cold water and ingested with a syringe or medicine dropper. Call your doctor for medical advice about side effects. Role of diet pills and cold remedies." Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ferri FF. Therapy with acetaminophen should be administered cautiously, if at all, in patients who consume three or more alcoholic drinks a day. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Hetlioz (tasimelteon)." Diphenhydramineis a common ingredient in sleeping aids; it is also used to treat allergies. doi:10.1093/sleep/zsy183, Culpepper L, Wingertzahn MA. Before having surgery, tell your doctor or dentist that you are taking this medication. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. (1985): 688-91, Williams DM "Phenylpropanolamine hydrochloride" Am Pharm NS30 Ask a doctor or pharmacist before using Dramamine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Is Dramamine useful to treat nausea or dry heaving? You can use the study as a second opinion to make health care decisions. (1986): 138-9, Prescott LF, Critchley JA "Drug interactions affecting analgesic toxicity." What conditions does Vicks DayQuil oral treat? Ask your doctor or pharmacist about using this product safely. Brand names: Dramamine, Driminate, Triptone Sleep aids available without a prescription can be effective for an occasional sleepless night. Check the labels on all your medications carefully to make sure you are not taking more than one product with the same ingredient(s). Warnings Follow all directions on your medicine label and package. Washington, DC: American Pharmaceutical Association information is beneficial, we may combine your email and website usage information with Moderate Potential Hazard, High plausibility. Liquid forms of some narcotics can be enhanced by mixing with antacids or sodium bicarbonate, which lengthens the high. When present, obstructive sleep apnea should be identified and treated. (2016): Schuller DE, Turkewitz D "Adverse effects of antihistamines." A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. (2001): "Product Information. Clin Pharmacol Ther 16 Opioids are common forms of drugs. Skip the missed dose if it is almost time for your next scheduled dose. Pills: Bonine (which is chewable) contains . Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. A concentrated solution can also be added to chewing gum with a liquid center; the liquid with concentrated drug may then be added to antacid tablets or sugar cubes. (1979): 175-6, Frewin DB, Leonello PP, Frewin ME "Hypertension after ingestion of Trimolets." In this case, though, the sleepiness effect is considered a downside of using the drug to tame allergy symptoms. Over-the-counter agents for the treatment of occasional disturbed sleep or transient insomnia: a systematic review of efficacy and safety. The consequences of abusing opiates include: Mixing opiates with potentiators can, at the very least, increase exposure and raise the risk of overdose. J Allergy Clin Immunol 73 N Engl J Med 280 (1989): 427-32, Lake CR, Zaloga G, Clymer R, Quirk RM, Chernow B "A double dose of phenylpropanolamine causes transient hypertension." Cumulative use of strong anticholinergics and incident dementia: a prospective cohort study. This effect is beneficial for those who turn to over-the-counter sleeping pills to treat insomnia. Applicable conditions: Chronic Obstructive Pulmonary Disease. Ask your doctor or pharmacist how much acetaminophen is safe to take. Systematic Reviews. Consult your pharmacist or local waste disposal company. Therapy with sympathomimetic agents should be administered cautiously in patients with diabetes mellitus. If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. Purdue Pharma LP Glaxo Wellcome Flaxer JM, et al. Applicable conditions: Asthma. (1990): 85-91, Chin C, Choy M "Cardiomyopathy induced by phenylpropanolamine." Do not use with any other drug containing acetaminophen without asking your doctor or pharmacist first. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. generic drugs) are not considered. Dosage form: capsule, liquid filled Ingredients: Acetaminophen 325mg, Dextromethorphan Hydrobromide 15mg, Doxylamine succinate 6.25mg Labeler: Lil' Drug Store Products, Inc. NDC code: 66715-9713 In Canada - Call your doctor for medical advice about side effects. To provide you with the most relevant and helpful information, and understand which Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. (1979): 427-31, Venkataramanan R, Kalp K, Rabinovitch M, et al. Different individuals may respond to medication in different ways. Moderate Potential Hazard, High plausibility. (1995): 301, Nelson EB, Temple AR "Acetaminophen hepatotoxicity, fasting, and ethanol." (1994): Lee KY, Beilin LJ, Vandongen R "Severe hypertension after ingestion of an appetite suppressant (phenylpropanolamine) with indomethacin." Moderate Potential Hazard, Moderate plausibility. 2019;67(4):674-694. doi:10.1111/jgs.15767, Gray SL, Anderson ML, Dublin S, et al. Unisom (doxylamine)." American Journal of Geriatric Psychiatry. This may relate to the time it takes for the medication to start working and how long it stays in the body. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, emphysema), diabetes, glaucoma, heart problems, high blood pressure, kidney problems, liver disease, overactive thyroid (hyperthyroidism), trouble urinating (such as due to enlarged prostate), use/abuse of alcohol. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product. Severe liver injury, including cases of acute liver failure resulting in liver transplant and death, has been reported in patients using acetaminophen. (1991): 376-81, O'Connell MB, Gross CR "The effect of single-dose phenylpropanolamine on blood pressure in patients with hypertension controlled by beta blockers." Do not increase your dose or take this medication more often than directed without your doctor's approval. Patients should be monitored for any changes in mood or behavior. Get medical help right away if you take too much acetaminophen (overdose), even if you feel well. Since Dramamine is used when needed, you may not be on a dosing schedule. Pfizer U.S. Pharmaceuticals Group Dramamine(881 reports) Common Nyquil side effects: Fatigue (feeling of tiredness): 108 reports Nasopharyngitis (inflammation of the nasopharynx): 108 reports Common Dramamine side effects: Dizziness: 119 reports Nausea (feeling of having an urge to vomit): 133 reports How the study uses the data? LIL' DRUG STORE PRODUCTS, INC., 1201 CONTINENTAL PLACE NECEDAR RAPIDS, IA 52402, Nighttime Relief Highly clinically significant. The rates are highest in the 25-54 age range, while over 1,000 people are treated in emergency rooms every day for opioid-related issues. These effects are usually transient and slight but may be significant with dosages higher than those normally recommended. (1980): 35-6, Bruno A, Nolte KB, Chapin J "Stroke associated with ephedrine use." In addition to lifestyle changes, your provider might recommend behavior therapy. In contrast, the newer, relatively nonsedating antihistamines (e.g., cetirizine, fexofenadine, loratadine) reportedly have low to minimal anticholinergic activity at normally recommended dosages and may be appropriate alternatives. Benadryl (diphenhydramine)." Am J Emerg Med 5 Abbott Pharmaceutical (1987): 1886,1890, Fallis RJ, Fisher M "Cerebral vasculitis and hemorrhage associated with phenylpropanolamine." The use of potentiators is exacerbating the issue of opiate abuse. This medication list is not intended to be complete and additional brand names may be found for each medication. The most common OTC medicine that could do this is probably diphenhydramine, the active ingredient in medicines like Benadryl, which . Moderate Potential Hazard, Moderate plausibility. (1972): 492-3, Frewin DB "Phenylpropanolamine. "Adverse cardiovascular events temporally associated with ma huang, an herbal source of ephedrine." (1986): 2636-7, Seeff LB, Cuccherini BA, Zimmerman HJ, Adler E, Benjamin SB "Acetaminophen hepatotoxicity in alcoholics." Death can occur from the misuse of antihistamines in very young children. Clin Pharmacokinet 10 Kryger MH, et al., eds. Sandoz Pharmaceuticals Corporation Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Many people using this medication do not have serious side effects. Medisca Inc Moderate Potential Hazard, Moderate plausibility. Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Fine L. Pharmacologic approach to insomnia. Belsomra (suvorexant)." Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products or diet aids). 2019; doi:10.1186/s13643-019-1163-9. We comply with the HONcode standard for trustworthy health information. Winkelman JW. But lifestyle changes are usually the best approach for chronic insomnia. Eur J Clin Pharmacol 15 Applicable conditions: Cardiovascular Disease, Hyperthyroidism, Hypotension. J Clin Pharmacol 26 (2001): "Product Information. The aspartame/phenylalanine content should be considered when these products are used in patients who must restrict their intake of phenylalanine (i.e. Chronic alcohol abusers may be at increased risk of hepatotoxicity during treatment with acetaminophen (APAP). Wyeth-Ayerst Laboratories AdCare Hospital Outpatient - Multiple Cities, AdCare Rhode Island Outpatient - Multiple Cities, Resolutions Recovery Residences - Multiple Cities, The editorial staff of American Addiction Centers is made up of credentialed clinical reviewers with hands-on experience in or expert knowledge of ad , Understanding Addiction: Research Studies, State-Funded Drug and Alcohol Rehab Centers, Family members and friends gather to discuss the problem with the person who is abusing opiates, CBT sessions can help clients recognize the triggers that lead to opiate abuse, Dangers of Snorting, Smoking, or Injecting Vicodin, Painkiller Addiction, Symptoms & Rehab Treatment, Clonidine Addiction: Side Effects, Withdrawal & Signs of Overdose, Carisoprodol (Soma) Addiction, Side Effects & Treatment, Dangers of Mixing Opiates & Benzodiazepines: Vicodin, Xanax, Oxycodone & Valium. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Sympathomimetic agents can induce transient mydriasis via stimulation of alpha-1 adrenergic receptors. It has been combined with hydrocodone, codeine, or dihydrocodeine. Dramamine II can reduce nausea for those who take opiates. At the same time, it can enhance the desired effects. A variety of abnormal thinking and behavior changes have been reported to occur in association with the use of most anxiolytics, sedatives and hypnotics. Is it time for a nonprescription sleep aid? Brandon Peters, MD, is a board-certified neurologist and sleep medicine specialist. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. J Neurol Neurosurg Psychiatry 45 Tacaryl (methdilazine)." You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Int J Aging Hum Dev. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Apothecon Inc J Pharmacokinet Biopharm 3 (1974): 1066-76, Paton DM, Webster DR "Clinical pharmacokinetics of H1-receptor antagonists (the antihistamines)." Dr. Antoneta, Doctor 9,004 Satisfied Customers Family Doctor at ABC Health Center Dr. Antoneta is online now Related Medical Questions M Javid, MD ABIM Certification Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). D&C Yellow No. Otherwise, call a poison control center right away. Patients should be warned not to exceed the maximum recommended total daily dosage of acetaminophen (4 g/day in adults and children 12 years of age or older), and to read all prescription and over-the-counter medication labels to ensure they are not taking multiple acetaminophen-containing products, or check with a healthcare professional if they are unsure. Consult your doctor before breast-feeding. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Many appear to be primarily metabolized by the liver, and both parent drugs and metabolites are excreted in the urine. information highlighted below and resubmit the form. Alternative methods of taking opiates can enhance the effects. If you have any questions, consult your pharmacist. Bristol-Myers Squibb muscle weakness. 2016;38(11):2340-2372. doi:10.1016/j.clinthera.2016.09.010. Ann Emerg Med 28 DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. * Approximation only. The phase IV clinical study analyzes what interactions people who take Dramamine and Nyquil have. If you need to take more than one medication at a time, always check the labels and be sure you aren't taking multiple medications with the same or similar active ingredients. J Pharm Sci 73 Some of these changes include decreased inhibition, aggressiveness, agitation, and hallucinations. It is not known whether Dramamine will harm an unborn baby. They are used for pain relief and often prescribed by doctors. US residents can call their local poison control center at 1-800-222-1222. (2001): "Product Information. Dramamine may cause blurred vision and may impair your thinking or reactions. https://www.uptodate.com/contents/search. Precedex (dexmedetomidine)." McNeil Pharmaceutical It is evident that the problem of opiate abuse is not going away. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. (2001): "Product Information. In general, anxiolytics, sedatives and hypnotics are extensively metabolized by the liver. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Severe Interactions These medications are not usually taken together. Dextromethorphan is a cough suppressant that affects a certain part of the brain (cough center), reducing the urge to cough. Dramamine has active ingredients of dimenhydrinate. Prescription sleeping pills: What's right for you? During pregnancy, this medication should be used only if clearly needed. There are 339 drugs known to interact with Vyvanse (lisdexamfetamine), along with 11 disease interactions, and 3 alcohol/food interactions. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. At the same time, it can enhance the desired effects. Philadelphia, PA: Elsevier. (1982): 458-64, Bruce RB, Turnbull LB, Newman JH, Pitts JE "Metabolism of brompheniramine." Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. If it is near the time of the next dose, skip the missed dose. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Wyeth-Ayerst Laboratories Drixoral (dextromethorphan)." Improper use of this medication (abuse) may result in serious harm (such as brain damage, seizure, death). Hydrocodone and oxycodone, for example, can be evaporated using cold water extraction. Every patient is different and you may need to take one of these medications despite caution against it. (1979): 1110-1, Gibson GJ, Warrell DA "Hypertensive crises and phenylpropanolamine." phenylketonurics). 13,274 people who take Nyquil and Dramamine are studied. Ambien (zolpidem)." Eur J Clin Pharmacol 14 (2001): Watemberg NM, Roth KS, Alehan FK, Epstein CE "Central anticholinergic syndrome on therapeutic doses of cyproheptadine." The dosage is based on your age. Management of insomnia and long-term use of sedative-hypnotic drugs in older patients. In doing so, diphenhydramine can cause sleepiness. Fraunfelder FT, Fraunfelder FW; Randall JA "Drug-Induced Ocular Side Effects" Boston, MA: Butterworth-Heinemann the unsubscribe link in the e-mail. This site complies with the HONcode standard for trustworthy health information: verify here. Different individuals may respond to medication in different ways. These could be signs of a serious condition. International Journal of Pharmacy Practice. While effective, the risk of serious diphenhydramine side effectsincluding confusion, dizziness, urinary retention, and liver or kidney issuesis increased in people age 65 and older. Tell your doctor if your condition lasts for more than 1 week, if it gets worse, or if it occurs with headache that doesn't go away, rash, or fever lasting more than 3 days. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Dramamine II can reduce nausea for those who take opiates. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Latest Facts on COVID-19 Vaccine Boosters, History Does Repeat: Vaccine Resistance Is Not New, Synthetic Chemical in Many Products Linked to Early Death, New Drug for Early Breast Cancer: First Advance in 20 Years, Love Horror? This is not a complete list of side effects and others may occur. Growing evidence suggests chronic use of these medications may also be associated with the long-term development of dementia. Get medical help right away if you have any very serious side effects, including: chest pain, fast/irregular heartbeat. Muscle relaxants, such as cyclobenzaprine (brand name Flexeril). Over-the-counter medications containing diphenhydramine and doxylamine used by older adults to improve sleep. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. (1986): 399-404, McClain CJ, Kromhout JP, Peterson FJ, Holtzman JL "Potentiation of acetaminophen hepatotoxicity by alcohol." Verywell Health's content is for informational and educational purposes only. Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine). Even shrooms which I've done twice. Int J Clin Pharmacol Ther Toxicol 28 Review of safety and efficacy of sleep medicines in older adults. Minimally clinically significant. Dramamine Nyquil Dramamine and Nyquil drug interactions - a phase IV clinical study of FDA data Summary: Drug interactions are reported only by a few people who take Dramamine and Nyquil together. This survey is being conducted by the WebMD marketing sciences department. (1995): 301, Zimmerman HJ, Maddrey WC "Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure." Document Id: 1843dbea-0c03-4ccc-8af3-c3658ac607eb, Set id: 9631ae65-aa73-4ca2-965c-89163d673aa9, or NyQuil products, carefully read each label to insure correct dosing, acetaminophen, dextromethorphan hydrobromide, and doxylamine succinate capsule, liquid filled. (2002): "Product Information. (2022): Leo PJ, Hollander JE, Shih RD, Marcus SM "Phenylpropanolamine and associated myocardial injury." Glaxo Wellcome All information is observation-only. Most sleep aids available without a prescription contain antihistamines.
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